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As a fallible process since its origins,1 peer review continues to be a widely debated aspect of modern science.2 Most scientists, if not all, are familiar with the infamous “reviewer #2” (R#2), synonymous with the “bad” reviewer, notorious for excessive or nonsensical demands. The internet is filled with jokes and sketches about R#2, and most readers have likely encountered a few. While it is not always R#2, this reviewer is often blamed and, interestingly, commonly perceived as male.3 Even the most diligent and competent reviewers have likely been labeled as R#2 at some point.

While there is no consensus on the origins of peer review, most authors agree that the Royal Society of London and its renowned publication, Philosophical Transactions - established in 1665 and edited by Henry Oldenburg - represent one of the earliest well-documented examples of peer review.4 Naturally, the modern peer review process, as we know it today, differs significantly from its origin. Like any evolving process, it demands ongoing assessment to identify strengths and areas for improvement. The Journal of the Brazilian Chemical Society (JBCS), as an international peer-reviewed journal, is equally committed to this effort.

As an experienced author, I have encountered almost every form of peer review throughout my career. Some reviews were appreciated, whereas others left me deeply
frustrated - even stung by certain comments from the reviewers. I had works accepted without corrections (a rare exception), manuscripts reviewed by up to seven different reviewers, and, like any seasoned scientist, I also faced rejections during the peer-review process. My experience as an author is no different from that of any experienced researcher in this matter. While reviewers’ comments were often justified, there were times when, from my admittedly biased perspective as an author, their recommendations to reject my work felt unwarranted. Despite the inevitable disappointment of rejection, appeals were rare exceptions throughout my academic journey.

By contrast, I am also an experienced reviewer, having written nearly 1,500 reports over the past 25 years, by my estimation. A simple calculation indicates an average of one review provided per week. In fact, I am confident I have exceeded this average. At present, I also serve as an editor responsible for overseeing and refining the peer-review process for manuscripts submitted to the JBCS and another journal, where I act as an Associate Editor. Like any editor of prestigious journals, I understand both the challenges inherent in this task and its critical importance, not only for the JBCS but also for authors and reviewers.

Given my experience and current role, it is fair to ask whether I have been impartial in all my recommendations. Of course, this is a rhetorical question, as I have always strived to provide the most technical and impartial reports possible. However, this does not imply that every recommendation I made was flawless, though I believe most were accurate. I have certainly been occasionally labeled as R#2 - the “hated person” - in some of the reports I have written. But I still stand by my assessments in nearly all of them. As a human being, I am aware that I also have biases. All reviewers have biases, whether conscious or unconscious. In fact, there are some insightful reports that describe the most common biases the peer review process is susceptible to.5,6 We - the JBCS editors - all experienced authors and reviewers, are acutely aware of the ongoing review crisis. We are also sensitive to biases, unintentional mistakes, and our own limitations.

Finding reviewers who are genuinely committed to providing scientifically sound and respectful reports - while fostering an honest dialogue between scientists - has become increasingly challenging. Ideally, these reports would be delivered promptly and received well by authors, a scenario every editor managing a submission would dream of. However, knowing the reality, we understand the challenges of securing even two usable reports within a short timeframe. This underscores the need to reevaluate and improve our editorial practices, particularly in selecting reviewers, handling reviews, making decisions, and addressing author appeals.

The selection of reviewers, a topic of great interest to most editors, will be managed internally by the JBCS editorial team.7 However, the handling of received reviews and appeals is of significant interest to our readers, particularly the authors who choose the JBCS as the venue for publishing their work. New recommendations for reviewers, an updated template for authors, revised requirements for compound and material characterization, and restructured JBCS guidelines can be found on our website. Now, let us focus on the peer review process and how we plan to improve and modernize it at the JBCS.

Rejecting a manuscript often demands more effort from both editors and reviewers than accepting one.8 Just considering the routine of identifying and contacting reviewers, as well as managing the review crisis, is enough to make any editor anxious - much like any reviewer receiving yet another email asking them to review a submission. To ease the burden on reviewers (and on ourselves), the JBCS editors are committed to improving our practices in several areas. We plan to make decisions more swiftly and increase the rate of desk rejections. But do not worry! If you are submitting a high-quality contribution to the JBCS, your work is more than welcome. However, as we aim to elevate both the quality and impact of the works we publish, our rejection and desk-rejection rates are likely to rise. These changes, ultimately, will enhance our journal. We are indeed making every effort to facilitate the review process and streamline the overall publication workflow. Our goal is to foster a positive relationship with reviewers, including R#2.

After implementing these changes and continuing to modernize and enhance the JBCS, we expect authors to carefully consider the feedback they receive. However, there may still be occasions when you, as an author, perceive R#2 as the villain and disagree with the review recommendation or the editor’s decision. In such cases, you may submit a technical appeal to the JBCS, which will be forwarded to me, as Editor-in-Chief, for thorough consideration. As an experienced editor as well (nearly 12 years of practice), I ask you to allow me to offer a few suggestions for these situations, outlining what to write and what not to write in an appeal. I am also assuming that you have selected the most appropriate journal for your work and that it fits the journal’s scope. Also, you have ensured that your work indeed has the novelty and impact required for publication.

(i) After emotions settle, reconsider whether the reviewer’s criticism - possibly made by R#2 - was valid. This is logical, but it does not mean it is easy, even for the most experienced authors. After that, reevaluate your work with a critical perspective and submit an appeal only once you are fully convinced that your manuscript merits publication.

(ii) Examine all reports carefully and determine whether the arguments for rejection were scientifically justified. If you decide to write an appeal, be technical and concise in your response. Long texts do not imply technical or authoritative knowledge. In general, editors prefer short texts.

(iii) Avoid lecturing the editor (and R#2); instead, focus on key technical points and  explain your disagreement. It is very important to facilitate the editors’ work;  therefore, reproduce each comment and prepare a response that is polite, authoritative, technically rigorous, critical, concise, and persuasive. Editors certainly know researchers capable of evaluating your appeal, if necessary.

(iv) Address each criticism raised by reviewers - especially those from R#2 - point by point. Copy and paste all comments to facilitate the editor’s work. Do not “forget” to include all comments. Leaving any comment out of your rebuttal letter will not be well received.

(v) An admirable curriculum is not equivalent to being right. I have received appeals in which the appellant assumes that describing their curriculum confers authority or implies correctness. Science does not care about curricula, but about what is technically correct. In research, as we all should know, the central concern is correctness, not the identity of who is correct.9 Citing the number of
publications, h-index, citation counts, awards, etc., is therefore useless in an appeal.

(vi) If you receive a second “no”, move on and use your energy to submit your improved manuscript to another journal. Do not mistake persistence for annoyance or nuisance.

(vii) A golden tip: Be polite. Again, be polite. Remember that R#2 is human too and may have made a mistake. Using offensive language toward a referee (or an editor) in an appeal (or in any other context) is unprofessional and clearly counterproductive.

It is well known that the success rates of appeals in prestigious journals are generally low.10 Whether or not your appeal succeeds, remember that, as a scientist, you may occasionally be labeled as R#2 yourself. While you have the right to agree or disagree, you certainly do not want to be cursed by authors whose work you reviewed kindly. So, avoid doing the same when you receive a negative recommendation from R#2. Instead, strive to build a collaborative and fruitful relationship with all reviewers - especially with R#2! Less hate, more love!

Brenno A. D. Netoa,b

Editor-in-chief of the Journal of the Brazilian Chemical Society
aLaboratório de Química Medicinal e Tecnológica, Instituto de Química (IQ), Universidade de Brasília (UnB), Campus Universitário Darcy Ribeiro, 70910-900 Brasília-DF, Brazil
bMolecular Sciences Graduate Program, Universidade Estadual de Goiás (UEG),
75132-400 Anápolis-GO, Brazil

https://orcid.org/0000-0003-3783-9283

References

  1. Adam, D.; Nature 2024, 634, 761. [Crossref]
  2. Tumin, D.; Tobias, J. D.; Saudi J. Anaesth. 2019, 13, S52. [Crossref]
  3. Peterson, D. A. M.; Soc. Sci. Q. 2020, 101, 1648. [Crossref]
  4. Spier, R.; Trends Biotechnol. 2002, 20, 357. [Crossref]
  5. Severin, A.; Martins, J.; Heyard, R.; Delavy, F.; Jorstad, A.; Egger, M.; BMJ Open 2020, 10, e035058. [Crossref]
  6. Lee, C. J.; Sugimoto, C. R.; Zhang, G.; Cronin, B.; J. Am. Soc. Inf. Sci. Tec. 2013, 64, 2. [Crossref]
  7. Carvalho da Silva, F.; J. Braz. Chem. Soc. 2026, 37, e20260005. [Crossref]
  8. Gölitz, P.; Angew. Chem., Int. Ed. 2016, 55, 13621. [Crossref]
  9. Herman, I. P.; Nature 2007, 445, 228. [Crossref]
  10. Weiss, P. S.; ACS Nano 2014, 8, 1951. [Crossref]

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